beta Catenin 抗体
Quick Overview for beta Catenin 抗体 (ABIN7249752)
抗原
See all beta Catenin (CATNB) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- Monoclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein corresponding to Mouse beta-catenin
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亚型
- IgG
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应用备注
- WB 1:500-1:1000, IHC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 420 μg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- beta Catenin (CATNB) (Catenin, beta (CATNB))
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别名
- Catenin beta
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背景
- CTNNB1,also known as β-Catenin,is an evolutionarily conserved,multifunctional intracellular protein. CTNNB1 was originally identified in cell adherens junctions (Ajs) where it functions to bridge the cytoplasmic domain of cadherins to a-catenin and the actin cytoskeleton. Besides its essential role in the Ajs,CTNNB1 is also a key downstream component of the canonical Wnt pathway that plays diverse and critical roles in embryonic development and adult tissue homeostasis. Deregulation of CTNNB1 activity is associated with multiple diseases including cancers. .
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分子量
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Observed_MW: 92 kDa
Calculated_MW: 92 kDa
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UniProt
- P35222, Q02248, Q9WU82
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途径
- Peptide Hormone Metabolism
抗原
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