CDC25A 抗体
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- 抗原 See all CDC25A 抗体
- CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDC25A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- KLH conjugated Synthetic peptide corresponding to Mouse Cdc25A
- 亚型
- IgG
- Top Product
- Discover our top product CDC25A Primary Antibody
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- 应用备注
- WB 1:500-1:1000, IHC 1:500-1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.96 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))
- 别名
- CDC25A (CDC25A 产品)
- 背景
- CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.
- 分子量
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Observed_MW: 70 kDa
Calculated_MW: 65-70 kDa
- UniProt
- P30304, P48965, P48964
- 途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase
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