XAB2 抗体
Quick Overview for XAB2 抗体 (ABIN7004725)
抗原
See all XAB2 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Antigen affinity purification
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免疫原
- Synthetic peptide of human XAB2
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亚型
- IgG
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anti-XPA Binding Protein 2 (XAB2) (AA 1-855) antibody
XAB2 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 1D1-1A9 unconjugated
anti-XPA Binding Protein 2 (XAB2) (AA 750-840) antibodyXAB2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-XPA Binding Protein 2 (XAB2) antibodyXAB2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-XPA Binding Protein 2 (XAB2) (N-Term) antibodyXAB2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-XPA Binding Protein 2 (XAB2) (C-Term) antibodyVerified XAB2 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-XPA Binding Protein 2 (XAB2) (C-Term) antibodyXAB2 适用: 人, 小鼠, 大鼠, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-XPA Binding Protein 2 (XAB2) (AA 35-84) antibodyXAB2 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马, Pig, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-XPA Binding Protein 2 (XAB2) (C-Term) antibodyXAB2 适用: 人, 小鼠, 大鼠, Cow, 犬, Drosophila melanogaster WB 宿主: 兔 Polyclonal unconjugated
anti-XPA Binding Protein 2 (XAB2) (N-Term) antibodyXAB2 适用: 人, 小鼠, 大鼠, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, ELISA 1:5000-1:10000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.6 mg/mL
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缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- XAB2 (XPA Binding Protein 2 (XAB2))
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别名
- XAB2
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背景
- HCNP, also known as XAB2 (Xeroderma pigmentosum group A (XPA) binding protein 2), HCRN, SYF1 or NTC90, is a nuclear protein that participates in transcription, transcription-coupled repair (TCR) and pre-mRNA splicing. It contains fifteen tetratricopeptide repeat motifs and associates with nucleotide excision repair machinery. More specifically, HCNP associates with Cockayne syndrome group A and B proteins (CSA and CSB), RNA Polymerase II (Pol II) and XPA in response to DNA damage and is believed to function in the TCR pathway. HCNP also functions as an essential component of a pre-mRNA splicing complex of the spliceosome (composed of AQR (aquarius), PRP19, CCDC16, HCNP, ISY1 and Cyclophilin E) and is required for proper RNA synthesis in the cell. In addition, HCNP functions as a component of the RAR corepressor complex with RAR and HDAC3 and exhibits an inhibitory effect on ATRA-induced cell differentiation. This suggests that HCNP may function as useful target in cancer therapy.
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分子量
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Observed_MW: Refer to figures
Calculated_MW: 100 kDa
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UniProt
- Q9HCS7
抗原
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