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- 抗原 See all XAB2 抗体
- XAB2 (XPA Binding Protein 2 (XAB2))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This XAB2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Antigen affinity purification
- 免疫原
- Synthetic peptide of human XAB2
- 亚型
- IgG
- Top Product
- Discover our top product XAB2 Primary Antibody
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anti-XPA Binding Protein 2 (XAB2) (AA 1-855) antibody
XAB2 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 1D1-1A9 unconjugated
anti-XPA Binding Protein 2 (XAB2) (AA 750-840) antibodyXAB2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-XPA Binding Protein 2 (XAB2) (N-Term) antibodyXAB2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-XPA Binding Protein 2 (XAB2) (C-Term) antibodyVerified XAB2 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-XPA Binding Protein 2 (XAB2) antibodyXAB2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-XPA Binding Protein 2 (XAB2) (AA 35-84) antibodyXAB2 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马, Pig, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-XPA Binding Protein 2 (XAB2) (C-Term) antibodyXAB2 适用: 人, 小鼠, 大鼠, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.4 mg/mL
- 缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- XAB2 (XPA Binding Protein 2 (XAB2))
- 别名
- XAB2 (XAB2 产品)
- 别名
- Dmel\\CG6197 antibody, Prp5 antibody, XAB2 antibody, Xab2 antibody, zgc:63498 antibody, zgc:63949 antibody, HCNP antibody, HCRN antibody, NTC90 antibody, SYF1 antibody, 0610041O14Rik antibody, AV025587 antibody, Ath55 antibody, fandango antibody, XPA binding protein 2 antibody, XPA binding protein 2 L homeolog antibody, fand antibody, xab2 antibody, XAB2 antibody, xab2.L antibody, Xab2 antibody
- 背景
- HCNP, also known as XAB2 (Xeroderma pigmentosum group A (XPA) binding protein 2), HCRN, SYF1 or NTC90, is a nuclear protein that participates in transcription, transcription-coupled repair (TCR) and pre-mRNA splicing. It contains fifteen tetratricopeptide repeat motifs and associates with nucleotide excision repair machinery. More specifically, HCNP associates with Cockayne syndrome group A and B proteins (CSA and CSB), RNA Polymerase II (Pol II) and XPA in response to DNA damage and is believed to function in the TCR pathway. HCNP also functions as an essential component of a pre-mRNA splicing complex of the spliceosome (composed of AQR (aquarius), PRP19, CCDC16, HCNP, ISY1 and Cyclophilin E) and is required for proper RNA synthesis in the cell. In addition, HCNP functions as a component of the RAR corepressor complex with RAR and HDAC3 and exhibits an inhibitory effect on ATRA-induced cell differentiation. This suggests that HCNP may function as useful target in cancer therapy.
- 分子量
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Observed_MW: Refer to figures
Calculated_MW: 100 kDa
- UniProt
- Q9HCS7
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