电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

SPTA1 抗体

This anti-SPTA1 antibody is a 兔 多克隆 antibody detecting SPTA1 in WB, IHC 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN7248185
发货至: 中国

Quick Overview for SPTA1 抗体 (ABIN7248185)

抗原

See all SPTA1 抗体
SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

适用

  • 67
  • 12
  • 5
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 39
  • 29

克隆类型

  • 55
  • 13
多克隆

标记

  • 29
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SPTA1 antibody is un-conjugated

应用范围

  • 50
  • 48
  • 40
  • 8
  • 6
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Synthetic peptide of human SPTA1

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:60-1:450, ELISA 1:5000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.7 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

    别名

    SPTA1

    背景

    Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia.

    分子量

    Observed_MW: Refer to figures

    Calculated_MW: 280 kDa

    UniProt

    P02549

    途径

    Regulation of Actin Filament Polymerization
You are here:
Chat with us!