TRAF6 抗体
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- 抗原 See all TRAF6 抗体
- TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRAF6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Antigen affinity purification
- 免疫原
- Fusion protein of human TRAF6
- 亚型
- IgG
- Top Product
- Discover our top product TRAF6 Primary Antibody
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anti-TNF Receptor-Associated Factor 6 (TRAF6) (AA 153-423) antibody
TRAF6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 6 (TRAF6) (AA 413-522) antibodyTRAF6 适用: 人 WB, ELISA, RNAi, PLA 宿主: 小鼠 Monoclonal 1B2 unconjugated
anti-TNF Receptor-Associated Factor 6 (TRAF6) (AA 1-522) antibodyTRAF6 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 6 (TRAF6) (AA 263-522) antibodyTRAF6 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 6 (TRAF6) (Middle Region) antibodyTRAF6 适用: 人, 小鼠, 大鼠, Cow, Pig, 兔, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 6 (TRAF6) (AA 441-530) antibodyTRAF6 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 6 (TRAF6) (AA 314-343) antibodyTRAF6 适用: 人 WB 宿主: 兔 Polyclonal RB40708 unconjugated
anti-TNF Receptor-Associated Factor 6 (TRAF6) (AA 1-522) antibodyTRAF6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 6 (TRAF6) (AA 1-522) antibodyTRAF6 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 6 (TRAF6) (C-Term) antibodyTRAF6 适用: 人, 小鼠 WB, IHC, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.54 mg/mL
- 缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))
- 别名
- TRAF6 (TRAF6 产品)
- 背景
- The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from, members of the TNF receptor superfamily. This protein mediates signaling from members of the TNF receptor superfamily as well as the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. This protein also interacts with the transforming growth factor (TGF) beta receptor complex and is required for Smad-independent activation of the JNK and p38 kinases. This protein has an amino terminal RING domain which is followed by four zinc-finger motifs, a central coiled-coil region and a highly conserved carboxyl terminal domain, known as the TRAF-C domain. Two alternatively spliced transcript variants, encoding an identical protein, have been reported.
- 分子量
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Observed_MW: Refer to figures
Calculated_MW: 60 kDa
- UniProt
- Q9Y4K3
- 途径
- NF-kappaB Signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Hepatitis C, Toll-Like Receptors Cascades, Ubiquitin Proteasome Pathway
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