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HLA-DRA 抗体

This anti-HLA-DRA antibody is a 兔 多克隆 antibody detecting HLA-DRA in IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7244882
发货至: 中国

Quick Overview for HLA-DRA 抗体 (ABIN7244882)

抗原

See all HLA-DRA 抗体
HLA-DRA (HLA Class II DR alpha (HLA-DRA))

适用

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宿主

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克隆类型

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多克隆

标记

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This HLA-DRA antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), ELISA
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen affinity purification

    免疫原

    Synthetic peptide of human HLA-DRA

    亚型

    IgG
  • 应用备注

    IHC 1:50-1:100, ELISA 1:5000-1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.9 mg/mL

    缓冲液

    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    HLA-DRA (HLA Class II DR alpha (HLA-DRA))

    别名

    HLA-DRA

    背景

    HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.

    UniProt

    P01903

    途径

    TCR Signaling, CXCR4-mediated Signaling Events, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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