SPAG1 抗体
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北京 101111
Quick Overview for SPAG1 抗体 (ABIN7242443)
抗原
See all SPAG1 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Synthetic peptide of human SPAG1
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亚型
- IgG
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anti-Sperm Associated Antigen 1 (SPAG1) (AA 1-365) antibody
SPAG1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 1 (SPAG1) antibodySPAG1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 1 (SPAG1) (AA 175-283) antibodySPAG1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Sperm Associated Antigen 1 (SPAG1) (AA 124-152), (N-Term) antibodySPAG1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB24228 unconjugated
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应用备注
- WB 1:500-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.3 mg/mL
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缓冲液
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- SPAG1 (Sperm Associated Antigen 1 (SPAG1))
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别名
- SPAG1
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背景
- The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman. Furthermore, immunization of female rats with the recombinant human protein reduced fertility. This protein localizes to the plasma membrane of germ cells in the testis and to the post-acrosomal plasma membrane of mature spermatozoa. Recombinant polypeptide binds GTP and exhibits GTPase activity. Thus, this protein may regulate GTP signal transduction pathways involved in spermatogenesis and fertilization. Two transcript variants of this gene encode the same protein.
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分子量
- 104 kDa
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NCBI登录号
- NP_003105
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UniProt
- Q07617
抗原
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