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- 抗原 See all SPAG1 抗体
- SPAG1 (Sperm Associated Antigen 1 (SPAG1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SPAG1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen affinity purification
- 免疫原
- Synthetic peptide of Human SPAG1
- 亚型
- IgG
- Top Product
- Discover our top product SPAG1 Primary Antibody
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anti-Sperm Associated Antigen 1 (SPAG1) (AA 1-365) antibody
SPAG1 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 1 (SPAG1) antibodySPAG1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Sperm Associated Antigen 1 (SPAG1) (AA 175-283) antibodySPAG1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Sperm Associated Antigen 1 (SPAG1) (AA 124-152), (N-Term) antibodySPAG1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB24228 unconjugated
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- 应用备注
- ELISA:1:1000-1:5000, IHC:1:25-1:100,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- SPAG1 (Sperm Associated Antigen 1 (SPAG1))
- 别名
- SPAG1 (SPAG1 产品)
- 别名
- cb1089 antibody, MGC162178 antibody, wu:fj78g10 antibody, sp75 antibody, tpis antibody, hsd-3.8 antibody, HSD-3.8 antibody, SP75 antibody, TPIS antibody, sperm associated antigen 1 antibody, sperm associated antigen 1a antibody, SPAG1 antibody, spag1a antibody, CpipJ_CPIJ006297 antibody, spag1 antibody, Spag1 antibody
- 背景
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Background: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman. Furthermore, immunization of female rats with the recombinant human protein reduced fertility. This protein localizes to the plasma membrane of germ cells in the testis and to the post-acrosomal plasma membrane of mature spermatozoa. Recombinant polypeptide binds GTP and exhibits GTPase activity. Thus, this protein may regulate GTP signal transduction pathways involved in spermatogenesis and fertilization. Two transcript variants of this gene encode the same protein.
Aliases: SPAG1 antibody, Sperm-associated antigen 1 antibody, HSD-3.8 antibody, Infertility-related sperm protein Spag-1 antibody
- UniProt
- Q07617
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