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SPAG1 抗体 (N-Term)

SPAG1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB24228 unconjugated
产品编号 ABIN651886
发货至: 中国
  • 抗原 See all SPAG1 抗体
    SPAG1 (Sperm Associated Antigen 1 (SPAG1))
    抗原表位
    • 9
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 124-152, N-Term
    适用
    • 29
    • 1
    • 1
    • 1
    宿主
    • 28
    • 1
    克隆类型
    • 29
    多克隆
    标记
    • 12
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SPAG1 antibody is un-conjugated
    应用范围
    • 21
    • 16
    • 16
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This SPAG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-152 amino acids from the N-terminal region of human SPAG1.
    克隆位点
    RB24228
    亚型
    Ig Fraction
    Top Product
    Discover our top product SPAG1 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    SPAG1 (Sperm Associated Antigen 1 (SPAG1))
    别名
    SPAG1 (SPAG1 产品)
    别名
    cb1089 antibody, MGC162178 antibody, wu:fj78g10 antibody, sp75 antibody, tpis antibody, hsd-3.8 antibody, HSD-3.8 antibody, SP75 antibody, TPIS antibody, sperm associated antigen 1 antibody, sperm associated antigen 1a antibody, SPAG1 antibody, spag1a antibody, CpipJ_CPIJ006297 antibody, spag1 antibody, Spag1 antibody
    背景
    The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman. Furthermore, immunization of female rats with the recombinant human protein reduced fertility. This protein localizes to the plasma membrane of germ cells in the testis and to the post-acrosomal plasma membrane of mature spermatozoa. Recombinant polypeptide binds GTP and exhibits GTPase activity. Thus, this protein may regulate GTP signal transduction pathways involved in spermatogenesis and fertilization. Two transcript variants of this gene encode the same protein. [provided by RefSeq].
    分子量
    103639
    基因ID
    6674
    NCBI登录号
    NP_003105, NP_757367
    UniProt
    Q07617
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