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LIM Domain Kinase 1 抗体

The 兔 多克隆 anti-LIM Domain Kinase 1 antibody (ABIN7239173) specifically detects LIM Domain Kinase 1 in ELISA 和 IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7239173
发货至: 中国
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Quick Overview for LIM Domain Kinase 1 抗体 (ABIN7239173)

抗原

See all LIM Domain Kinase 1 (LIMK1) 抗体
LIM Domain Kinase 1 (LIMK1)

适用

  • 107
  • 77
  • 72
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 103
  • 19
  • 3

克隆类型

  • 106
  • 19
多克隆

标记

  • 59
  • 9
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  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This LIM Domain Kinase 1 antibody is un-conjugated

应用范围

  • 89
  • 48
  • 27
  • 26
  • 26
  • 18
  • 15
  • 8
  • 7
  • 6
  • 6
  • 3
  • 1
  • 1
  • 1
ELISA, Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Synthetic peptide of human LIMK1

    亚型

    IgG
  • 应用备注

    IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.9 mg/mL

    缓冲液

    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    LIM Domain Kinase 1 (LIMK1)

    别名

    LIMK1

    背景

    There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is a serine/threonine kinase that regulates actin polymerization via phosphorylation and inactivation of the actin binding factor cofilin. This protein is ubiquitously expressed during development and plays a role in many cellular processes associated with cytoskeletal structure.

    NCBI登录号

    NP_002305

    UniProt

    P53667

    途径

    Caspase Cascade in Apoptosis, Regulation of Cell Size, CXCR4-mediated Signaling Events
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