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Pleiotrophin 抗体

This anti-Pleiotrophin antibody is a 兔 多克隆 antibody detecting Pleiotrophin in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7238324
发货至: 中国

Quick Overview for Pleiotrophin 抗体 (ABIN7238324)

抗原

See all Pleiotrophin (PTN) 抗体
Pleiotrophin (PTN)

适用

  • 78
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  • 3
  • 3
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  • 2
  • 2
  • 2
人, 小鼠, 大鼠

宿主

  • 101
  • 9
  • 2
  • 2

克隆类型

  • 103
  • 11
多克隆

标记

  • 48
  • 16
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  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Pleiotrophin antibody is un-conjugated

应用范围

  • 74
  • 38
  • 26
  • 26
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  • 20
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  • 16
  • 8
  • 5
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Synthetic peptide of human PTN

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.3 mg/mL

    缓冲液

    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Pleiotrophin (PTN)

    别名

    PTN

    背景

    Pleiotrophin(PTN) also known asheparin-binding brain mitogen(HBBM) orheparin-binding growth factor 8(HBGF-8) orneurite growth-promoting factor 1(NEGF1) orheparin affinity regulatory peptide(HARP) orheparin binding growth associated molecule(HB-GAM) is aproteinthat in humans is encoded by thePTNgene.Pleiotrophin is an 18- kDagrowth factorthat has a high affinity forheparin. It is structurally related tomidkineandretinoic acid induced heparin-binding protein. Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation.

    分子量

    19 kDa

    NCBI登录号

    NP_002816

    UniProt

    P21246

    途径

    RTK signaling
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