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Patched 1 抗体

This anti-Patched 1 antibody is a 兔 多克隆 antibody detecting Patched 1 in WB, ELISA 和 IHC. Suitable for 人 和 小鼠.
产品编号 ABIN7235487
发货至: 中国

Quick Overview for Patched 1 抗体 (ABIN7235487)

抗原

See all Patched 1 (PTCH1) 抗体
Patched 1 (PTCH1)

适用

  • 40
  • 27
  • 9
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 37
  • 7
  • 4

克隆类型

  • 42
  • 6
多克隆

标记

  • 36
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Patched 1 antibody is un-conjugated

应用范围

  • 34
  • 23
  • 19
  • 11
  • 8
  • 6
  • 5
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human PTCH1

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Patched 1 (PTCH1)

    别名

    PTCH1

    背景

    This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently.

    分子量

    161 kDa

    UniProt

    Q13635

    途径

    Hedgehog Signaling, Carbohydrate Homeostasis, Tube Formation
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