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IL-6 Receptor 抗体

This anti-IL-6 Receptor antibody is a 兔 多克隆 antibody detecting IL-6 Receptor in WB 和 IHC. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7234279
发货至: 中国

Quick Overview for IL-6 Receptor 抗体 (ABIN7234279)

抗原

See all IL-6 Receptor (IL6R) 抗体
IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

适用

人, 大鼠, 小鼠

宿主

  • 58
  • 25
  • 5
  • 1

克隆类型

  • 59
  • 29
  • 1
多克隆

标记

  • 63
  • 18
  • 5
  • 1
  • 1
  • 1
This IL-6 Receptor antibody is un-conjugated

应用范围

  • 69
  • 41
  • 33
  • 28
  • 25
  • 20
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Antigen Affinity Purification

    免疫原

    Recombinant Human Interleukin-6 receptor subunit alpha protein

    亚型

    IgG
  • 应用备注

    WB 1:1000-1:2000 IHC 1:100-1:300

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.05 % Proclin300 and 50 % glycerol, pH 7.4.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

    别名

    IL6R

    背景

    This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.

    分子量

    Observed_MW: 80 kDa

    Calculated_MW: 40,51 kDa

    UniProt

    P08887

    途径

    JAK/STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints
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