MAPT 抗体 (AA 34-368)
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- Key Features
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- High quality MAPT Primary Antibody for the detection of MAPT.
- Reliable product with high standard validation data
- 抗原 See all MAPT 抗体
- MAPT (Microtubule-Associated Protein tau (MAPT))
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抗原表位
- AA 34-368
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MAPT antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)
- 原理
- Polyclonal Antibody to Tau Protein (MAPT)
- 特异性
- The antibody is a rabbit polyclonal antibody raised against MAPT. It has been selected for its ability to recognize MAPT in immunohistochemical staining and western blotting.
- 交叉反应
- 小鼠
- 纯化方法
- Antigen-specific affinity chromatography followed by Protein A affinity chromatography
- 免疫原
- Recombinant Tau Protein (MAPT) corresdonding to Ala34~Ser368 with N-terminal His Tag
- 亚型
- IgG
- Top Product
- Discover our top product MAPT Primary Antibody
- Product Specific Information
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- What can the MAPT Antibody ABIN7434482 be used for?
- This polyclonal MAPT Antibody detects MAPT. The MAPT Antibody has been validated for various applications and can be used for the detection of MAPT and derivatives by Western Blotting, Immunohistochemistry, Immunoprecipitation, Immunocytochemistry.
- What validation data is available for this MAPT Antibody?
- The Primary Antibody has currently 5 product images that show its performance in a variety of applications. The product is currently available in 1 mL, 20 μL, 100 μL, 200 μL quantities. MAPT Antibody for the detection of MAPT and derivatives.
- What is the function of MAPT?
- This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008].
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- 应用备注
- Western blotting: 0.5-2 μg/mL,Immunohistochemistry: 5-20 μg/mL,Immunocytochemistry: 5-20 μg/mL,Optimal working dilutions must be determined by end user.
- 说明
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The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium azide, 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
- 有效期
- 24 months
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- 抗原
- MAPT (Microtubule-Associated Protein tau (MAPT))
- 别名
- MAPT (MAPT 产品)
- 背景
- DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, Neurofibrillary tangle protein, Microtubule Associated Protein Tau, Paired helical filament-tau, G Protein Beta1/Gamma2 Subunit-Interacting Factor 1
- UniProt
- P19332
- 途径
- MAPK Pathway, Microtubule Dynamics, M Phase, Regulation of Cell Size
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