RIPK3 抗体 (C-Term)
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北京 101111
Quick Overview for RIPK3 抗体 (C-Term) (ABIN6992283)
抗原
See all RIPK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Several isoforms of hRIP3 are known to exist.
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纯化方法
- hRIP3 Antibody is affinity chromatography purified via peptide column.
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免疫原
- Anti-hRIP3 antibody was raised against a peptide corresponding to 18 amino acids near the carboxy terminus of human hRIP3. The immunogen is located within the last 50 amino acids of hRIP3.
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亚型
- IgG
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anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (N-Term) antibody
RIPK3 适用: 人, 小鼠, 大鼠, Cow, Pig, 马, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 61-91) antibodyRIPK3 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 16-239) antibodyRIPK3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 489-518) antibodyRIPK3 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) antibodyRIPK3 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 1-217) antibodyRIPK3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 1-518) antibodyRIPK3 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 1-120) antibodyRIPK3 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 168-217) antibodyRIPK3 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Receptor-Interacting serine-threonine Kinase 3 (RIPK3) (AA 61-91) antibodyRIPK3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB8634 unconjugated
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应用备注
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WB: 0.5-1 μ,g/mL, IF: 20 μ,g/mL, IHC: 2-5 μ,g/mL.
Antibody validated: Western Blot, Immunofluorescence and Immunohistochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- hRIP3 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- hRIP3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
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别名
- hRIP3
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背景
- HRIP3 Antibody: Certain serine/threonine protein kinases, such as ASK1, RIP, DAP, and ZIP kinases, are mediators of apoptosis. Receptor interacting proteins including RIP and RIP2/RICK mediate apoptosis induced by TNFR1 and Fas, two prototype members in the death receptor family. A novel member in the RIP kinase family was recently identified and designated RIP3. RIP3 contains N-terminal kinase domain but, unlike RIP or RIP2, lacks the C-terminal death or CARD domain. RIP3 binds to RIP and TNFR1, mediates TNFR1 induced apoptosis, and attenuates RIP and TNFR1 induced NF-?B activation. Overexpression of RIP3 induces apoptosis and NF-?B activation. The messenger RNA of RIP3 is expressed in a subset of adult tissues.
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分子量
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Predicted: 57kD
Observed: 57 kD kDa -
基因ID
- 11035
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UniProt
- Q9Y572
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途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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