RIPK3 抗体 (N-Term)
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北京 101111
Quick Overview for RIPK3 抗体 (N-Term) (ABIN2777333)
抗原
See all RIPK3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- RIPK3 Antibody - N-terminal region
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序列
- GGSQSGTGSG EPGGTLGYLA PELFVNVNRK ASTASDVYSF GILMWAVLAG
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预测反应
- Cow: 79%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 86%, Rat: 91%
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产品特性
- This is a rabbit polyclonal antibody against RIPK3. It was validated on Western Blot and immunohistochemistry.
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纯化方法
- Protein A purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human RIPK3
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8110155
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).
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- RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
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别名
- RIPK3
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背景
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Background Information: RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
Gene Name: Receptor-interacting serine-threonine kinase 3
Alternative Symbols: RIP3
Protein Name: Receptor-interacting serine/threonine-protein kinase 3
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分子量
- 57 kDa
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基因ID
- 11035
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NCBI登录号
- NP_006862
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UniProt
- Q9Y572
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途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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