SOX10 抗体 (N-Term)
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北京 101111
Quick Overview for SOX10 抗体 (N-Term) (ABIN6992183)
抗原
See all SOX10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- SOX10 Antibody is predicted to not cross-react with other SOX familiy members.
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纯化方法
- SOX10 Antibody is affinity chromatography purified via peptide column.
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免疫原
- SOX10 antibody was raised against a peptide corresponding to 18 amino acids near the amino terminus of human SOX10.
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亚型
- IgG
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应用备注
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SOX10 antibody can be used for Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- SOX10 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- SOX10 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- SOX10 (SRY (Sex Determining Region Y)-Box 10 (SOX10))
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别名
- SOX10
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背景
- SOX10 Antibody: SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and the determination of the cell fate (1). The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins (2). This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development (2). Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschprung disease (3). SLC30A8 expression in beta-cells was found to be influenced by cytokine expression, particularly IFN-gamma and IL-1beta (4).
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分子量
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Predicted: 51 kDa
Observed: 54 kDa -
基因ID
- 6663
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NCBI登录号
- NP_008872
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UniProt
- P56693
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途径
- Chromatin Binding
抗原
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