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SOX10 抗体 (N-Term)

This anti-SOX10 antibody is a 兔 多克隆 antibody detecting SOX10 in WB, IF, ELISA 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6992183
发货至: 中国
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Quick Overview for SOX10 抗体 (N-Term) (ABIN6992183)

抗原

See all SOX10 抗体
SOX10 (SRY (Sex Determining Region Y)-Box 10 (SOX10))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This SOX10 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    N-Term

    特异性

    SOX10 Antibody is predicted to not cross-react with other SOX familiy members.

    纯化方法

    SOX10 Antibody is affinity chromatography purified via peptide column.

    免疫原

    SOX10 antibody was raised against a peptide corresponding to 18 amino acids near the amino terminus of human SOX10.

    亚型

    IgG
  • 应用备注

    SOX10 antibody can be used for Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    SOX10 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    SOX10 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    SOX10 (SRY (Sex Determining Region Y)-Box 10 (SOX10))

    别名

    SOX10

    背景

    SOX10 Antibody: SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and the determination of the cell fate (1). The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins (2). This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development (2). Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschprung disease (3). SLC30A8 expression in beta-cells was found to be influenced by cytokine expression, particularly IFN-gamma and IL-1beta (4).

    分子量

    Predicted: 51 kDa

    Observed: 54 kDa

    基因ID

    6663

    NCBI登录号

    NP_008872

    UniProt

    P56693

    途径

    Chromatin Binding
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