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UBD 抗体 (AA 80-130)

This anti-UBD antibody is a 兔 多克隆 antibody detecting UBD in WB, ELISA, IF 和 IHC (p). Suitable for 人.
产品编号 ABIN6992138
发货至: 中国

Quick Overview for UBD 抗体 (AA 80-130) (ABIN6992138)

抗原

See all UBD 抗体
UBD (Ubiquitin D (UBD))

适用

  • 52
  • 45
  • 21
  • 2
  • 2
  • 2
  • 1

宿主

  • 60
  • 5

克隆类型

  • 54
  • 11
多克隆

标记

  • 29
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This UBD antibody is un-conjugated

应用范围

  • 47
  • 22
  • 20
  • 18
  • 12
  • 6
  • 4
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 12
    • 9
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 80-130

    特异性

    UBD antibody is human specific.

    纯化方法

    UBD antibody is affinity chromatography purified via peptide column.

    免疫原

    UBD antibody was raised against a 16 amino acid peptide near the center of human UBD. The immunogen is located within amino acids 80 - 130 of UBD.

    亚型

    IgG
  • 应用备注

    UBD antibody can be used for detection of UBD by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    UBD antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    UBD antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    UBD (Ubiquitin D (UBD))

    别名

    UBD

    背景

    UBD, also designated ubiquitin D or diubiquitin, plays a role in antigen presentation, cytokine response and apoptosis. It is a 165 amino acid protein encoded in the major histocompatibility complex (MHC) that consists of two domains which share significant homology with ubiquitin (1,2). UBD is inducible by interferon gamma and TNF-alpha and regulates TNF-alpha-induced and LPS-mediated activation of the central mediator of innate immunity NF-kappa-B by promoting TNF-alpha-mediated proteasomal degradation of ubiquitinated-I-kappa-B-alpha (3). It may also regulate cell growth during dendritic cell or B cell activation and development (4,5).

    分子量

    Predicted: 18 kDa

    Observed: 17 kDa

    基因ID

    10537

    NCBI登录号

    NP_006389

    UniProt

    O15205

    途径

    Ubiquitin Proteasome Pathway
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