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SOX4 抗体 (N-Term)

This 兔 多克隆 anti-SOX4 antibody specifically detects SOX4 in WB, ELISA, IHC (p) 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN6992114
发货至: 中国
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Quick Overview for SOX4 抗体 (N-Term) (ABIN6992114)

抗原

See all SOX4 抗体
SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This SOX4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • 抗原表位

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    N-Term

    特异性

    SOX4 antibody is human, mouse and rat reactive.

    纯化方法

    SOX4 antibody is affinity chromatography purified via peptide column.

    免疫原

    SOX4 antibody was raised against a 16 amino acid peptide near the amino terminus of human SOX4. The immunogen is located within the first 50 amino acids of SOX4.

    亚型

    IgG
  • 应用备注

    SOX4 antibody can be used for detection of SOX4 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    SOX4 antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    SOX4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))

    别名

    SOX4

    背景

    SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate (1,2). It may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin) (3). SOX4 contains one HMG box DNA-binding domain and may function in the apoptosis pathway leading to cell death. It has also been suggested to play a role in tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development (4,5).

    分子量

    Predicted: 52 kDa

    Observed: 520 kDa

    基因ID

    6659

    NCBI登录号

    NP_003098

    UniProt

    Q06945
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