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SOX4 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects SOX4 in WB 和 IHC. It exhibits reactivity toward 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 斑马鱼, 山羊 和 马.
产品编号 ABIN2780469
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SOX4 抗体 (N-Term) (ABIN2780469)

抗原

See all SOX4 抗体
SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))

适用

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人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 斑马鱼, 山羊, 马

宿主

  • 54
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兔

克隆类型

  • 55
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多克隆

标记

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This SOX4 antibody is un-conjugated

应用范围

  • 44
  • 25
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    原理

    SOX4 Antibody - N-terminal region

    序列

    STASTGGKAD DPSWCKTPSG HIKRPMNAFM VWSQIERRKI MEQSPDMHNA

    特异性

    Peptide immunogen shares 93 % with human SOX11.

    预测反应

    Cow: 100%, Dog: 100%, Goat: 91%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against SOX4. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human SOX4
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP38234-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))

    别名

    SOX4

    背景

    Background Information: SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. It may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Gene Name: SRY (sex determining region Y)-box 4

    Alternative Symbols: CSS10, EVI16

    Protein Name: Transcription factor SOX-4

    分子量

    47 kDa

    基因ID

    6659

    NCBI登录号

    NP_003098

    UniProt

    Q06945
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