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- 抗原 See all SOX4 抗体
- SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SOX4 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Staining Methods (StM)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant full-length human SOX4 protein
- 克隆位点
- SOX4-2540
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product SOX4 Primary Antibody
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anti-SRY (Sex Determining Region Y)-Box 4 (SOX4) (AA 54-103) antibody
SOX4 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 4 (SOX4) (N-Term) antibodySOX4 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 斑马鱼, 山羊, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 4 (SOX4) (AA 86-114) antibodySOX4 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 4 (SOX4) (AA 86-114), (N-Term) antibodySOX4 适用: 人 WB, IHC (p), IF, FACS 宿主: 兔 Polyclonal RB18502 unconjugated
anti-SRY (Sex Determining Region Y)-Box 4 (SOX4) (AA 1-60) antibodySOX4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 4 (SOX4) (AA 45-136) antibodySOX4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 4 (SOX4) (AA 1-100) antibodySOX4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 4 (SOX4) (AA 269-297) antibodySOX4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 4 (SOX4) (AA 45-136) antibodySOX4 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2C5 unconjugated
anti-SRY (Sex Determining Region Y)-Box 4 (SOX4) (C-Term) antibodySOX4 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Positive Control: Breast or Colon Carcinoma.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))
- 别名
- SOX4 (SOX4 产品)
- 别名
- EVI16 antibody, AA682046 antibody, Sox-4 antibody, sox4 antibody, wu:fb82f08 antibody, wu:fq41g10 antibody, zgc:65850 antibody, zgc:77392 antibody, SRY-box 4 antibody, SRY box 4 antibody, SRY (sex determining region Y)-box 4 antibody, SRY (sex determining region Y)-box 4a antibody, SOX4 antibody, Sox4 antibody, sox4a antibody
- 背景
- SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors with a critical role in embryonic development and in cell-fate determination during organogenesis of the heart, pancreas, brain, and in B and T lymphocyte differentiation. SOX4 gene expression is upregulated in many cancer types, and increased SOX4 activity contributes to cellular transformation, cell survival, and metastasis. Gene expression profiling has uncovered SOX4 with upregulated activity during TGF--induced epithelial-mesenchymal transition (EMT) in normal and cancerous breast epithelial cells. SOX4 is indispensable for EMT and cell survival invitro and for primary tumor growth and metastasis invivo. SOX4 is identified as a master regulator of EMT by governing the expression of the epigenetic modifier Ezh2.
- 分子量
- 47kDa
- 基因ID
- 6659
- UniProt
- Q06945
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