ATG4B 抗体 (C-Term)
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北京 101111
Quick Overview for ATG4B 抗体 (C-Term) (ABIN6992096)
抗原
See all ATG4B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- ATG4B antibody is human, mouse and rat reactive. At least two isoforms of ATG4B are known to exist, this antibody will detect only the larger isoform. ATG4B is predicted to not cross-react with other ATG4 proteins.
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纯化方法
- ATG4B antibody is affinity chromatography purified via peptide column.
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免疫原
- ATG4B antibody was raised against a 17 amino acid peptide near the carboxy terminus of human ATG4B. The immunogen is located within the last 50 amino acids of ATG4B.
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亚型
- IgG
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anti-Autophagy related 4B Cysteine Peptidase (ATG4B) (AA 1-221) antibody
ATG4B 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 6C3C5 unconjugated
anti-Autophagy related 4B Cysteine Peptidase (ATG4B) (AA 1-221) antibodyATG4B 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 4H9A5 unconjugated
anti-Autophagy related 4B Cysteine Peptidase (ATG4B) (AA 350-400) antibodyATG4B 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4B Cysteine Peptidase (ATG4B) (AA 16-45), (N-Term) antibodyATG4B 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB7496 unconjugated
anti-Autophagy related 4B Cysteine Peptidase (ATG4B) (AA 358-390), (C-Term) antibodyATG4B 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal RB7560 unconjugated
anti-Autophagy related 4B Cysteine Peptidase (ATG4B) (AA 85-200) antibodyATG4B 适用: 人, 小鼠, 大鼠 ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4B Cysteine Peptidase (ATG4B) (AA 23-53), (N-Term) antibodyATG4B 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4B Cysteine Peptidase (ATG4B) antibodyATG4B 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Autophagy related 4B Cysteine Peptidase (ATG4B) antibodyATG4B 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Autophagy related 4B Cysteine Peptidase (ATG4B) (C-Term) antibodyATG4B 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, 豚鼠, 兔, 猴, 马, Bat, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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ATG4B antibody can be used for detection of ATG4B by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- ATG4B antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- ATG4B antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))
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别名
- ATG4B
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背景
- Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components (1,2). ATG4B, also known as AUTL1, is one of four mammalian orthologs of the yeast ATG4 protein, all four are cysteine proteases (3). ATG4 is required for ATG8 conjugation to phosphatidylethanolamine on autophagosomal membranes. In mammals, each ATG4 homolog shows a selective preference for the ATG8 homologs (4). ATG4B has been found to be a novel protective protein in inflammatory colitis (5).
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分子量
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Predicted: 43 kDa
Observed: 46 kDa -
基因ID
- 23192
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NCBI登录号
- NP_037457
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UniProt
- Q9Y4P1
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途径
- Autophagy
抗原
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