JAG1 抗体 (C-Term)
Quick Overview for JAG1 抗体 (C-Term) (ABIN6992092)
抗原
See all JAG1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- JAG1 antibody is human, mouse and rat reactive. At least two isoforms of JAG1 are known to exist, this antibody will detect both isoforms.
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纯化方法
- JAG1 antibody is affinity chromatography purified via peptide column.
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免疫原
- JAG1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human JAG1. The immunogen is located within the last 50 amino acids of JAG1.
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亚型
- IgG
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anti-Jagged 1 (JAG1) (N-Term) antibody
JAG1 适用: 人, 小鼠 WB, ELISA, IHC, IF, FM 宿主: 兔 Polyclonal unconjugated
anti-Jagged 1 (JAG1) (AA 47-212) antibodyJAG1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 7C7H2 unconjugated
anti-Jagged 1 (JAG1) (AA 47-212) antibodyJAG1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 6A9B2 unconjugated
anti-Jagged 1 (JAG1) (AA 836-1047) antibodyJAG1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Jagged 1 (JAG1) (AA 809-1046) antibodyJAG1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Jagged 1 (JAG1) antibodyJAG1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal J1G53-3 unconjugated
anti-Jagged 1 (JAG1) (AA 470-834) antibodyJAG1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Jagged 1 (JAG1) (AA 33-250) antibodyJAG1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Jagged 1 (JAG1) (AA 826-1084) antibodyJAG1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Jagged 1 (JAG1) (C-Term) antibodyVerified JAG1 适用: 人, 小鼠 ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
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应用备注
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JAG1 antibody can be used for detection of JAG1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- JAG1 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- JAG1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- JAG1 (Jagged 1 (JAG1))
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别名
- JAG1
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背景
- The LIN-12/Notch family of transmembrane receptors plays a central role in development by regulating cell fate decisions (1). Ligands for Notch include JAG1, JAG2 and Delta. JAG1 is one of the DSL (Delta, Serrate, Lag2) transmembrane proteins that can activate Notch. It is involved in mammalian cardiovascular development and in cell-fate decisions during hematopoiesis (1,2). JAG1 is widely expressed in adult and fetal tissues and the mutation of the JAG1 gene is associated with Familial Tetrology of Fallot (3). JAG1 expression is associated with prostate cancer metastasis and is up-regulated in cervical squamous cell carcinoma (4,5).
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分子量
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Predicted: 134 kDa
Observed: 130 kDa -
基因ID
- 182
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NCBI登录号
- NP_000205
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UniProt
- P78504
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途径
- Notch Signaling, Stem Cell Maintenance
抗原
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