ATG4C 抗体 (C-Term)
Quick Overview for ATG4C 抗体 (C-Term) (ABIN6992038)
抗原
See all ATG4C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- ATG4C antibody is human, mouse and rat reactive. ATG4C is predicted to not cross-react with other ATG4 proteins.
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纯化方法
- ATG4C antibody is affinity chromatography purified via peptide column.
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免疫原
- ATG4C antibody was raised against an 18 amino acid peptide near the carboxy terminus of human ATG4C. The immunogen is located within the last 50 amino acids of ATG4C.
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亚型
- IgG
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anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (AA 321-458) antibody
ATG4C 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E10H7 unconjugated
anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (AA 419-448) antibodyATG4C 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (N-Term) antibodyATG4C 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (AA 167-196) antibodyATG4C 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB7497 unconjugated
anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (AA 33-62), (N-Term) antibodyATG4C 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB7561 unconjugated
anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (AA 259-458) antibodyATG4C 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (AA 1-458) antibodyATG4C 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (AA 21-70) antibodyATG4C 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (AA 419-448), (C-Term) antibodyATG4C 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB7499 unconjugated
anti-Autophagy related 4C Cysteine Peptidase (ATG4C) (N-Term) antibodyATG4C 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ATG4C antibody can be used for detection of ATG4C by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- ATG4C antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- ATG4C antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- ATG4C (Autophagy related 4C Cysteine Peptidase (ATG4C))
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别名
- ATG4C
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背景
- Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components (1,2). ATG4C, also known as autophagin-3, is one of four mammalian orthologs of the yeast ATG4 protein, all four are cysteine proteases (3). Recent studies have shown that ATG4C and Beclin-1 are regulated by the microRNA miR-376b, overexpression of miR-376b led to decreased mRNA and protein levels, thereby blocking starvation and TOR inhibition-related autophagy (4).
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分子量
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Predicted: 50 kDa
Observed: 57 kDa -
基因ID
- 84938
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NCBI登录号
- NP_835739
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UniProt
- Q96DT6
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途径
- Autophagy
抗原
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