HDAC2 抗体 (C-Term)
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Quick Overview for HDAC2 抗体 (C-Term) (ABIN6992035)
抗原
See all HDAC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- HDAC2 antibody is human, mouse and rat reactive. At least two isoforms of HDAC2 are known to exist, this antibody will detect both isoforms. HDAC2 antibody is predicted to not cross-react with other members of the HDAC family.
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纯化方法
- HDAC2 antibody is affinity chromatography purified via peptide column.
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免疫原
- HDAC2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human HDAC2. The immunogen is located within the last 50 amino acids of HDAC2.
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亚型
- IgG
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应用备注
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HDAC2 antibody can be used for detection of HDAC2 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for Immunohistochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- HDAC2 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- HDAC2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- HDAC2 (Histone Deacetylase 2 (HDAC2))
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别名
- HDAC2
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背景
- The histone deacetylase (HDAC) family contains multiple members which are divided into four classes. Class I of the HDAC family comprises four members, HDAC1, 2, 3, and 8, each of which contains a deacetylase domain and exhibits a different, individual substrate specificity and function in vivo (1). HDAC2 was first identified as as a mammalian homolog to the yeast transcriptional regulator RPD3 (2). HDAC2 forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor (2,3). Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events (4).
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分子量
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Predicted: 54 kDa
Observed: 52 kDa -
基因ID
- 3066
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NCBI登录号
- NP_001518
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UniProt
- Q92769
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途径
- Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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