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FKBP1A 抗体

This anti-FKBP1A antibody is a 兔 多克隆 antibody detecting FKBP1A in WB, ELISA, ICC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6992004
发货至: 中国

Quick Overview for FKBP1A 抗体 (ABIN6992004)

抗原

See all FKBP1A 抗体
FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

适用

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人, 小鼠, 大鼠

宿主

  • 64
  • 9

克隆类型

  • 55
  • 18
多克隆

标记

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This FKBP1A antibody is un-conjugated

应用范围

  • 43
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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 特异性

    FKBP12 antibody is human, mouse and rat reactive.

    纯化方法

    FKBP12 antibody is affinity chromatography purified via peptide column.

    免疫原

    FKBP12 antibody was raised against an 18 amino acid peptide near the center of human FKBP12. The immunogen is located within the first 50 amino acids of FKBP12.

    亚型

    IgG
  • 应用备注

    FKBP12 antibody can be used for detection of FKBP12 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunocytochemistry at 5 μ,g/mL. For Immunoflorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    FKBP12 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    FKBP12 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

    别名

    FKBP12

    背景

    FKBP, or FK506 binding protein, is a family of proteins that have prolyl isomerase activity and are related to the cyclophilins in function (1). FKBP12, also called FKBP1, was originally identified as a target of FK506 and rapamycin activity and catalyzes the transition between cis and transproline residues critical for proper folding of proteins (2). FKBP12 is an abundant, evolutionarily conserved cytoplasmic protein that is an important regulator of diverse array of cellular processes including T cell activation, entry into the cell cycle and intracellular calcium release (3-5).

    分子量

    Predicted: 12 kDa

    Observed: 12 kDa

    基因ID

    2280

    NCBI登录号

    NP_463460

    UniProt

    P62942

    途径

    Negative Regulation of Transporter Activity, Methionine Biosynthetic Process
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