C19ORF80 抗体 (N-Term)
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北京 101111
Quick Overview for C19ORF80 抗体 (N-Term) (ABIN6991947)
抗原
See all C19ORF80 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-90, N-Term
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特异性
- Betatrophin antibody is human, mouse and rat reactive. At least three isoforms of Betatrophin are known to exist, this antibody will detect the two largest isoforms.
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纯化方法
- Betatrophin antibody is affinity chromatography purified via peptide column.
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免疫原
- Betatrophin antibody was raised against a 16 amino acid peptide near the amino terminus of human Betatrophin. The immunogen is located within amino acids 40 - 90 of Betatrophin.
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亚型
- IgG
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应用备注
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Betatrophin antibody can be used for detection of Betatrophin by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse and rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Betatrophin antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Betatrophin antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- C19ORF80 (Chromosome 19 Open Reading Frame 80 (C19ORF80))
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别名
- Betatrophin
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背景
- The Betatrophin protein, also known as the hepatocellular carcinoma-associated protein TD26, is an adipocyte- and liver-enriched insulin targeted gene that is thought to play a role in lipid metabolism be regulating serum triglyceride levels (1,2). Betatrophin is closely related to the angiopoietin-like (ANGPTL) protein family. Betatrophin mRNA increases in the cold environment and after treatment with a high-fat diet, while its mRNA levels decrease in response to fasting, suggesting that it may play a role in mediating thermogenesis and energy homeostasis (3).
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分子量
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Predicted: 22 kDa
Observed: 22 kDa -
基因ID
- 55908
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NCBI登录号
- NP_061157
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UniProt
- Q6UXH0
抗原
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