AIMP2 抗体 (AA 150-200)
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北京 101111
Quick Overview for AIMP2 抗体 (AA 150-200) (ABIN6991920)
抗原
See all AIMP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 150-200
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特异性
- AIMP2 antibody is human specific. AIMP2 antibody is predicted to not cross-react with AIMP1.
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纯化方法
- AIMP2 antibody is affinity chromatography purified via peptide column.
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免疫原
- AIMP2 antibody was raised against a 16 amino acid peptide near the center of human AIMP2. The immunogen is located within amino acids 150 - 200 of AIMP2.
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亚型
- IgG
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anti-Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2) (AA 201-300) antibody
AIMP2 适用: 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2) (AA 141-320) antibodyAIMP2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2) (AA 1-100) antibodyAIMP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8E7 unconjugated
anti-Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2) (AA 1-320) antibodyAIMP2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2) (AA 298-320), (Middle Region) antibodyAIMP2 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2) (AA 51-100) antibodyAIMP2 适用: 人, 大鼠, 小鼠, 犬, 豚鼠, 马, 绵羊, 猴, Hamster, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2) (AA 151-200) antibodyAIMP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2) (N-Term) antibodyAIMP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2) (AA 156-184) antibodyAIMP2 适用: 人 WB 宿主: 兔 Polyclonal RB17662 unconjugated
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应用备注
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AIMP2 antibody can be used for detection of AIMP2 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- AIMP2 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- AIMP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- AIMP2 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2))
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别名
- AIMP2
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背景
- AIMP2 was initially identified as a part of an aminoacyl-tRNA synthesase complex (1). It was later discovered to be a cofactor and substrate of Parkin, a Ring-type E3 ubiquitin ligase that is important for the survival of dopamine neurons in Parkinson's disease, accumulation of AIMP2 in these cells lead to catecholaminergic cell death (2). AIMP2 can also bind to TRAF2, a key player in the TNF-alpha signaling pathway, causing the ubiquitination of TRAF2 by cIAP1, leading to TNF-alpha-dependent apoptosis (3). Finally, AIMP2 has been suggested to function as a tumor suppressor (4).
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分子量
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Predicted: 35 kDa
Observed: 36 kDa -
基因ID
- 7965
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NCBI登录号
- NP_006294
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UniProt
- Q13155
抗原
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