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IL12A 抗体 (C-Term)

This anti-IL12A antibody is a 兔 多克隆 antibody detecting IL12A in WB, ELISA, IHC (p) 和 IF. Suitable for 人.
产品编号 ABIN6991911
发货至: 中国

Quick Overview for IL12A 抗体 (C-Term) (ABIN6991911)

抗原

See all IL12A 抗体
IL12A (Interleukin 12 alpha (IL12A))

适用

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宿主

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克隆类型

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多克隆

标记

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This IL12A antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
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    C-Term

    特异性

    IL-12A antibody is human specific. IL-12A antibody will not cross-react with IL-12B.

    纯化方法

    IL-12A antibody is affinity chromatography purified via peptide column.

    免疫原

    IL-12A antibody was raised against an 18 amino acid peptide near the carboxy terminus of human IL-12A. The immunogen is located within the last 50 amino acids of IL-12A.

    亚型

    IgG
  • 应用备注

    IL-12A antibody can be used for detection of IL-12A by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    IL-12A antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    IL-12A antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    IL12A (Interleukin 12 alpha (IL12A))

    别名

    IL-12A

    背景

    IL-12A is subunit of the cytokine IL-12 which acts on T- and natural killer cells, and has a broad array of biological activities. IL-12 is a disulfide-linked heterodimer composed of the 35-kD subunit and a 40-kD subunit that is a member of the cytokine receptor family (1). IL-12 is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells (1,2). The responses of lymphocytes to IL-12 are mediated by the activator of transcription protein STAT4 (2). Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity (3).

    分子量

    Predicted: 22 kDa

    Observed: 22 kDa

    基因ID

    3592

    NCBI登录号

    NP_000873

    UniProt

    P29459

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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