ULK2 抗体 (AA 480-530)
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北京 101111
Quick Overview for ULK2 抗体 (AA 480-530) (ABIN6991859)
抗原
See all ULK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 480-530
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特异性
- At least two isoforms of ULK2 are known to exist, this antibody will detect both isoforms. ULK2 antibody is predicted to not cross-react with ULK1.
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纯化方法
- ULK2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- ULK2 antibody was raised against a 17 amino acid peptide near the center of human ULK2 . The immunogen is located within amino acids 480 - 530 of ULK2.
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亚型
- IgG
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应用备注
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ULK2 Antibody can be used for detection of ULK2 by Western blot at 1 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- ULK2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- ULK2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- ULK2 (Unc-51 Like Kinase 2 (ULK2))
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别名
- ULK2
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背景
- ULK2 Antibody: ULK2, also known as ATG1B, is a key serine/threonine protein kinase probably acting at the most upstream step of autophagosome formation. Knockout of ULK2 results in a severe defect in the autophagy pathway. ULK2 is highly conserved among eukaryotes and shows high homology with its related protein ULK1. Both ULK1 and ULK2 form a complex with ATG13 and FIP200 that mediates TOR signaling and is essential for autophagy. Like ULK1, ULK2 is also thought to be involved in early neuronal growth and differentiation.
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分子量
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Predicted: 105, 114 kDa
Observed: 100 kDa -
基因ID
- 9706
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NCBI登录号
- NP_055498
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UniProt
- Q8IYT8
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途径
- Regulation of Cell Size, Autophagy
抗原
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