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ULK2 抗体 (AA 480-530)

This anti-ULK2 antibody is a 兔 多克隆 antibody detecting ULK2 in WB, ELISA, IHC (p) 和 IF. Suitable for 人.
产品编号 ABIN6991859
发货至: 中国

Quick Overview for ULK2 抗体 (AA 480-530) (ABIN6991859)

抗原

See all ULK2 抗体
ULK2 (Unc-51 Like Kinase 2 (ULK2))

适用

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宿主

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克隆类型

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多克隆

标记

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This ULK2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • 抗原表位

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    AA 480-530

    特异性

    At least two isoforms of ULK2 are known to exist, this antibody will detect both isoforms. ULK2 antibody is predicted to not cross-react with ULK1.

    纯化方法

    ULK2 Antibody is affinity chromatography purified via peptide column.

    免疫原

    ULK2 antibody was raised against a 17 amino acid peptide near the center of human ULK2 . The immunogen is located within amino acids 480 - 530 of ULK2.

    亚型

    IgG
  • 应用备注

    ULK2 Antibody can be used for detection of ULK2 by Western blot at 1 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    ULK2 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    ULK2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    ULK2 (Unc-51 Like Kinase 2 (ULK2))

    别名

    ULK2

    背景

    ULK2 Antibody: ULK2, also known as ATG1B, is a key serine/threonine protein kinase probably acting at the most upstream step of autophagosome formation. Knockout of ULK2 results in a severe defect in the autophagy pathway. ULK2 is highly conserved among eukaryotes and shows high homology with its related protein ULK1. Both ULK1 and ULK2 form a complex with ATG13 and FIP200 that mediates TOR signaling and is essential for autophagy. Like ULK1, ULK2 is also thought to be involved in early neuronal growth and differentiation.

    分子量

    Predicted: 105, 114 kDa

    Observed: 100 kDa

    基因ID

    9706

    NCBI登录号

    NP_055498

    UniProt

    Q8IYT8

    途径

    Regulation of Cell Size, Autophagy
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