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CD59 抗体 (N-Term)

This anti-CD59 antibody is a 兔 多克隆 antibody detecting CD59 in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN6991822
发货至: 中国

Quick Overview for CD59 抗体 (N-Term) (ABIN6991822)

抗原

See all CD59 抗体
CD59

适用

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人, 小鼠

宿主

  • 106
  • 95
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克隆类型

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  • 94
  • 1
多克隆

标记

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This CD59 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    N-Term

    纯化方法

    CD59 Antibody is affinity chromatography purified via peptide column.

    免疫原

    Rabbit polyclonal CD59 antibody was raised against a 14 amino acid peptide near the amino terminus of human CD59. The immunogen is located within the first 50 amino acids of CD59.

    亚型

    IgG
  • 应用备注

    CD59 antibody can be used for detection of CD59 by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    CD59 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    CD59 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    CD59

    别名

    CD59

    背景

    CD59 Antibody: The complement regulatory protein CD59 is a cell surface glycoprotein that regulates complement-mediated cell lysis and is involved in lymphocyte signal transduction. CD59 is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. CD59 also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and ultimately cerebral infarction.

    分子量

    14 kDa

    基因ID

    966

    NCBI登录号

    NP_000602

    UniProt

    P13987

    途径

    Complement System
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