CD59 抗体 (N-Term)
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北京 101111
Quick Overview for CD59 抗体 (N-Term) (ABIN6991822)
抗原
See all CD59 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- CD59 Antibody is affinity chromatography purified via peptide column.
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免疫原
- Rabbit polyclonal CD59 antibody was raised against a 14 amino acid peptide near the amino terminus of human CD59. The immunogen is located within the first 50 amino acids of CD59.
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亚型
- IgG
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应用备注
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CD59 antibody can be used for detection of CD59 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- CD59 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- CD59 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- CD59
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别名
- CD59
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背景
- CD59 Antibody: The complement regulatory protein CD59 is a cell surface glycoprotein that regulates complement-mediated cell lysis and is involved in lymphocyte signal transduction. CD59 is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. CD59 also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and ultimately cerebral infarction.
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分子量
- 14 kDa
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基因ID
- 966
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NCBI登录号
- NP_000602
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UniProt
- P13987
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途径
- Complement System
抗原
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