PDGFB 抗体 (C-Term)
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北京 101111
Quick Overview for PDGFB 抗体 (C-Term) (ABIN6991812)
抗原
See all PDGFB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- PDGF-B Antibody is affinity chromatography purified via peptide column.
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免疫原
- Rabbit polyclonal PDGF-B antibody was raised against a 19 amino acid peptide near the carboxy terminus of human PDGF-B. The immunogen is located within the last 50 amino acids of PDGF-B.
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亚型
- IgG
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应用备注
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PDGF-B antibody can be used for detection of PDGF-B by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PDGF-B Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- PDGF-B antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- PDGFB (Platelet Derived Growth Factor Subunit B (PDGFB))
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别名
- PDGF-B
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背景
- PDGF-B Antibody: The platelet-derived growth factor beta (PDGF-B) is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB). Mutations in this gene are associated with meningioma , and reciprocal translocations between chromosomes 22 and 7, at sites where the PDGF-B gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans.
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分子量
- Predicted: 27 kDa
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基因ID
- 5155
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NCBI登录号
- NP_002599
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UniProt
- P01127
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
抗原
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