ATG14 抗体 (AA 270-320)
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北京 101111
Quick Overview for ATG14 抗体 (AA 270-320) (ABIN6991757)
抗原
See all ATG14 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 270-320
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特异性
- At least three isoforms of ATG14 are known to exist, this antibody will detect all three isoforms
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纯化方法
- ATG14 Antibody is affinity chromatography purified via peptide column.
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免疫原
- ATG14 antibody was raised against an 18 amino acid synthetic peptide near the center of human ATG14. The immunogen is located within amino acids 270 - 320 of ATG14.
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亚型
- IgG
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应用备注
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ATG14 antibody can be used for detection of ATG14 by Western blot at 1 - 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- ATG14 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- ATG14 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- ATG14 (ATG14 Autophagy Related 14 (ATG14))
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别名
- ATG14
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背景
- ATG14 Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein ATG1. ATG14 is a subunit of a class III phosphatidylinositol (PtdIns) 3-kinase complex that targets the complex to the endoplasmic reticulum, the site of autophagosome formation.
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分子量
- 54 kDa
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基因ID
- 22863
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NCBI登录号
- NP_055739
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UniProt
- Q6ZNE5
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途径
- Autophagy
抗原
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