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Nibrin 抗体 (N-Term)

Name: Nibrin 抗体 (N-Term)
Brand: antibodies-online
SKU: ABIN6991690
Availability: OutOfStock

This anti-Nibrin antibody is a 兔多克隆 antibody detecting Nibrin in WB, ELISA, IF 和 IHC (p). Suitable for 人, 小鼠和大鼠.

产品编号 ABIN6991690

发货至: 中国

Quick Overview for Nibrin 抗体 (N-Term) (ABIN6991690)

抗原

See all Nibrin (NBN) 抗体

Nibrin (NBN)

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This Nibrin antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product NBN Primary Antibody

抗原表位
38

15

10

8

5

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 50-100, N-Term

特异性

At least three alternatively spliced transcript isoforms of NIBRIN are known to exist.

纯化方法

NIBRIN Antibody is affinity chromatography purified via peptide column.

免疫原

NIBRIN antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human NIBRIN. The immunogen is located within amino acids 50 - 100 of NIBRIN.

亚型

IgG
anti-Nibrin (NBN) (AA 467-615) antibody
NBN 适用: 人 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 7E4C2 unconjugated

anti-Nibrin (NBN) (AA 467-615) antibody
NBN 适用: 人, 大鼠 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 7E4A2 unconjugated

anti-Nibrin (NBN) (AA 183-460) antibody
NBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 8E7 unconjugated

anti-Nibrin (NBN) (AA 461-754) antibody
NBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3A9 unconjugated

anti-Nibrin (NBN) (AA 461-754) antibody
NBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3A2 unconjugated

anti-Nibrin (NBN) (AA 183-460) antibody
NBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 6E11 unconjugated

anti-Nibrin (NBN) (AA 183-460) antibody
NBN 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2F5 unconjugated

anti-Nibrin (NBN) (AA 435-754) antibody
NBN 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Nibrin (NBN) (AA 645-754) antibody
NBN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E4 unconjugated

anti-Nibrin (NBN) antibody
KO Validated NBN 适用: 人 WB, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated

应用备注

NIBRIN antibody can be used for detection of NIBRIN by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

NIBRIN Antibody is supplied in PBS containing 0.02 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C,4 °C

储存方法

NIBRIN antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
抗原

Nibrin (NBN)

别名

NIBRIN

背景

NIBRIN Antibody: NIBRIN (NBN) is a member of the double-strand break repair complex MRE11/RAD50/NBN (MRN) which is involved in DNA double-strand break repair, DNA damage-induced checkpoint activation and plays a critical role in the maintenance of chromosome integrity. NIBRIN contains two modules found in cell cycle checkpoint proteins, a forkhead-associated domain adjacent to a breast cancer carboxy-terminal domain. Mutations in this gene are associated with Nijmegen breakage syndrome and maybe the cause of cancer predisposition and aplastic anemia.

基因ID

4683

NCBI登录号

NP_002476

UniProt

O60934

途径

DNA Damage Repair, Production of Molecular Mediator of Immune Response