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Nkx2-2 抗体 (AA 90-140)

This 兔 多克隆 anti-Nkx2-2 antibody specifically detects Nkx2-2 in IF, WB, IHC (p) 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN6991653
发货至: 中国
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Quick Overview for Nkx2-2 抗体 (AA 90-140) (ABIN6991653)

抗原

See all Nkx2-2 抗体
Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Nkx2-2 antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
  • 抗原表位

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    AA 90-140

    特异性

    NKX2-2 antibody is predicted to not cross-react with other NK2 homeobox family members.

    纯化方法

    NKX2-2 Antibody is affinity chromatography purified via peptide column.

    免疫原

    NKX2-2 antibody was raised against a 19 amino acid synthetic peptide near the center of human NKX2-2. The immunogen is located within amino acids 90 - 140 of NKX2-2.

    亚型

    IgG
  • 应用备注

    NKX2-2 antibody can be used for detection of NKX2-2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    NKX2-2 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    NKX2-2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

    别名

    NKX2-2

    背景

    NKX2-2 Antibody: NKX2-2 (NK2 homeobox 2) is a member of a family of transcription factors that are involved in embryonic development and cell fate. NKX2-2 is crucial in the development of pancreatic islet cell differentiation and activates the ghrelin-promoter in these cells. NKX2-2 is expressed at the onset of pancreatic epithelium formation and becomes restricted to mature α,-, β,- and PP cells, and in NKX2-2-null mice embryos, all β,-cells and most a-cells are replaced by ghrelin-positive cells. NKX2-2 is also thought to be involved in ventral neuronal patterning and floor plate development and commissural axon guidance.

    基因ID

    4821

    NCBI登录号

    NP_002500

    UniProt

    O95096

    途径

    Dopaminergic Neurogenesis
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