Nkx2-2 抗体 (AA 90-140)
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Quick Overview for Nkx2-2 抗体 (AA 90-140) (ABIN6991653)
抗原
See all Nkx2-2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 90-140
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特异性
- NKX2-2 antibody is predicted to not cross-react with other NK2 homeobox family members.
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纯化方法
- NKX2-2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- NKX2-2 antibody was raised against a 19 amino acid synthetic peptide near the center of human NKX2-2. The immunogen is located within amino acids 90 - 140 of NKX2-2.
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亚型
- IgG
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应用备注
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NKX2-2 antibody can be used for detection of NKX2-2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- NKX2-2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- NKX2-2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
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别名
- NKX2-2
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背景
- NKX2-2 Antibody: NKX2-2 (NK2 homeobox 2) is a member of a family of transcription factors that are involved in embryonic development and cell fate. NKX2-2 is crucial in the development of pancreatic islet cell differentiation and activates the ghrelin-promoter in these cells. NKX2-2 is expressed at the onset of pancreatic epithelium formation and becomes restricted to mature α,-, β,- and PP cells, and in NKX2-2-null mice embryos, all β,-cells and most a-cells are replaced by ghrelin-positive cells. NKX2-2 is also thought to be involved in ventral neuronal patterning and floor plate development and commissural axon guidance.
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基因ID
- 4821
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NCBI登录号
- NP_002500
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UniProt
- O95096
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途径
- Dopaminergic Neurogenesis
抗原
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