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DISP1 抗体 (N-Term)

This anti-DISP1 antibody is a 兔 多克隆 antibody detecting DISP1 in WB, ELISA, IF 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN6991624
发货至: 中国

Quick Overview for DISP1 抗体 (N-Term) (ABIN6991624)

抗原

See all DISP1 抗体
DISP1 (Dispatched Homolog 1 (DISP1))

适用

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人, 小鼠

宿主

  • 6
  • 1

克隆类型

  • 7
多克隆

标记

  • 7
This DISP1 antibody is un-conjugated

应用范围

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  • 2
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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-70, N-Term

    特异性

    At least two isoforms of DISP1 are known to exist, this antibody will detect both isoforms. DISP1 antibody is predicted to not cross-react with EMX1.

    纯化方法

    DISP1 Antibody is affinity chromatography purified via peptide column.

    免疫原

    DISP1 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human DISP1. The immunogen is located within amino acids 20 - 70 of DISP1.

    亚型

    IgG
  • 应用备注

    DISP1 antibody can be used for detection of DISP1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    DISP1 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    DISP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    DISP1 (Dispatched Homolog 1 (DISP1))

    别名

    DISP1

    背景

    DISP1 Antibody: DISP1 is the mammalian homolog of the Drosophila Dispatched segment-polarity gene and a key regulator of the Hedgehog (Hh) signaling pathway during embryonic development. DISP1 is required to move Shh from site of synthesis during embryogenesis, mutations in the gene result in lethality at mid-gestation and prevents specification of ventral cell types in the neural tube. Recent results have shown that DISP1 mediates the basolateral secretion of Shh and regulates growth of mammalian long bones through the control of Ihh.

    基因ID

    84976

    NCBI登录号

    NP_116279

    UniProt

    Q96F81

    途径

    Hedgehog Signaling
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