PRICKLE1 抗体 (C-Term)
Quick Overview for PRICKLE1 抗体 (C-Term) (ABIN6991606)
抗原
See all PRICKLE1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Multiple isoforms of PRICKLE1 are known to exist. PRICKLE1 antibody is predicted to not cross-react with other PRICKLE protein family members.
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纯化方法
- PRICKLE1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- PRICKLE1 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human PRICKLE1. The immunogen is located within the last 50 amino acids of PRICKLE1.
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亚型
- IgG
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anti-Prickle-Like Protein 1 (PRICKLE1) (AA 684-756) antibody
PRICKLE1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8G5 unconjugated
anti-Prickle-Like Protein 1 (PRICKLE1) (AA 684-756) antibodyPRICKLE1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Prickle-Like Protein 1 (PRICKLE1) (C-Term) antibodyPRICKLE1 适用: 人, 大鼠, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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PRICKLE1 antibody can be used for detection of PRICKLE1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunofluorescence starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PRICKLE1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- PRICKLE1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))
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别名
- PRICKLE1
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背景
- PRICKLE1 Antibody: PRICKLE1, also known as RILP or EPM1B, is a Disheveled-associated protein that serves as a nuclear translocation receptor for REST/NRSF and REST4 (1, 2). It contains three N-terminal LIM domains and three C-terminal nuclear localization signals. It localizes to the cytoplasm, as well as to the nuclear membrane and expressed at higher levels in placenta. PRICKLE1 is a negative regulator of the Wnt / beta-catenin signaling pathway and is a putative tumor suppressor in human HCCs. Defects in the gene encoding PRICKLE1 are associated with autosomal recessive progressive myoclonic epilepsy.
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分子量
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Predicted: 46, 91 kDa
Observed: 52, 90 kDa -
基因ID
- 144165
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NCBI登录号
- NP_694571
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UniProt
- Q96MT3
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途径
- WNT signaling, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development, Protein targeting to Nucleus
抗原
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