NLRX1 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for NLRX1 抗体 (N-Term) (ABIN6991399)
抗原
See all NLRX1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 70-120, N-Term
-
纯化方法
- NOD5 Antibody is affinity chromatography purified via peptide column.
-
免疫原
- NOD5 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human NOD5. The immunogen is located within amino acids 70 - 120 of NOD5.
-
亚型
- IgG
-
-
-
-
应用备注
-
NOD5 antibody can be used for detection of NOD5 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- NOD5 Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- NOD5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
-
- NLRX1 (NLR Family Member X1 (NLRX1))
-
别名
- NOD5
-
背景
- NOD5 Antibody: NOD5, also known as NLRX1, is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD5 localizes to the mitochondrial outer membrane and interacts with the virus-induced signaling adapter protein VISA. Unlike a subset of NOD-like receptors (NLRs) such as NOD1 and NOD2 which trigger pro-inflammatory cascades, and other NLRs that induce the caspase 1 inflammasome in response to immune challenges, NOD5 amplifies NF-κ,B and JNK pathways by inducing reactive oxygen species production.
-
基因ID
- 79671
-
NCBI登录号
- NP_078894
-
UniProt
- Q86UT6
-
途径
- SARS-CoV-2 Protein Interactome
抗原
-