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IDH2 抗体 (N-Term)

This anti-IDH2 antibody is a 兔 多克隆 antibody detecting IDH2 in WB, ELISA, IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6991363
发货至: 中国

Quick Overview for IDH2 抗体 (N-Term) (ABIN6991363)

抗原

See all IDH2 抗体
IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This IDH2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    N-Term

    纯化方法

    IDH2 Antibody is affinity chromatography purified via peptide column.

    免疫原

    IDH2 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human IDH2. The immunogen is located within the first 50 amino acids of IDH2.

    亚型

    IgG
  • 应用备注

    IDH2 antibody can be used for detection of IDH2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    IDH2 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    IDH2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    IDH2 (Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2))

    别名

    IDH2

    背景

    IDH2 Antibody: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Two NADP(+)-dependent isocitrate dehydrogenases have been found as homodimer: IDH1 is predominantly cytosolic and peroxisomal and IDH2 is mitochondrial. Both IDH1 and IDH2 play significant roles in the tricarboxylic acid cycle (TCA), and defects in IDH1 as well as IDH2 have been implicated in the development of glioma as well as other malignancies.

    基因ID

    3418

    NCBI登录号

    NP_002159

    UniProt

    P48735

    途径

    Warburg Effect
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