RIMS3 抗体 (N-Term)
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北京 101111
Quick Overview for RIMS3 抗体 (N-Term) (ABIN6990855)
抗原
See all RIMS3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 60-110, N-Term
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特异性
- This antibody is predicted to have no cross-reactivity to other Rim proteins.
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纯化方法
- Rim3 Antibody is affinity chromatography purified via peptide column.
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免疫原
- Rim3 antibody was raised against a 17 amino acid synthetic peptide from near the amino terminus of human Rim3. The immunogen is located within amino acids 60 - 110 of Rim3.
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亚型
- IgG
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anti-Regulating Synaptic Membrane Exocytosis 3 (RIMS3) (C-Term) antibody
RIMS3 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, Cow, 豚鼠, 马, 兔, Bat, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Regulating Synaptic Membrane Exocytosis 3 (RIMS3) (C-Term) antibodyRIMS3 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Regulating Synaptic Membrane Exocytosis 3 (RIMS3) antibodyRIMS3 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Regulating Synaptic Membrane Exocytosis 3 (RIMS3) (N-Term) antibodyRIMS3 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Rim3 antibody can be used for detection of Rim3 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rim3 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Rim3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- RIMS3 (Regulating Synaptic Membrane Exocytosis 3 (RIMS3))
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别名
- Rim3
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背景
- Rim3 Antibody: Rab3-interacting molecules (RIMs) are synaptic proteins are synaptic proteins necessary for neural transmission and plasticity. While both Rim1 and Rim 2 are thought to be effector proteins for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner, less is known of Rim3. Expression of Rim3 in PC12 cells induced a significant increase in calcium-triggered exocytosis, with no appreciable change in the baseline release, suggesting that it plays a role in the regulation of exocytosis. Rim3 protein localizes primarily to neuronal dendrites and the postsynaptic densities, as opposed to Rim1 which is found in presynapse locations, indicating that Rim3 may contribute to synapse transmission and plasticity.
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基因ID
- 9783
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NCBI登录号
- NP_055562
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UniProt
- Q9UJD0
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途径
- Stem Cell Maintenance, Synaptic Vesicle Exocytosis
抗原
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