UIMC1 抗体 (N-Term)
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北京 101111
Quick Overview for UIMC1 抗体 (N-Term) (ABIN6990793)
抗原
See all UIMC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-80, N-Term
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纯化方法
- RAP80 Antibody is affinity chromatography purified via peptide column.
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免疫原
- RAP80 antibody was raised against a 17 amino acid synthetic peptide from near the amino terminus of human RAP80. The immunogen is located within amino acids 30 - 80 of RAP80.
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亚型
- IgG
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anti-Ubiquitin Interaction Motif Containing 1 (UIMC1) (AA 1-230) antibody
UIMC1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Interaction Motif Containing 1 (UIMC1) (AA 161-235) antibodyUIMC1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Interaction Motif Containing 1 (UIMC1) (C-Term) antibodyUIMC1 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Interaction Motif Containing 1 (UIMC1) (N-Term) antibodyUIMC1 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Interaction Motif Containing 1 (UIMC1) (AA 1-385) antibodyUIMC1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Interaction Motif Containing 1 (UIMC1) (AA 567-601), (C-Term) antibodyUIMC1 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB48354 unconjugated
anti-Ubiquitin Interaction Motif Containing 1 (UIMC1) (Internal Region) antibodyVerified UIMC1 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Ubiquitin Interaction Motif Containing 1 (UIMC1) antibodyUIMC1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Interaction Motif Containing 1 (UIMC1) (AA 1-385) antibodyUIMC1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin Interaction Motif Containing 1 (UIMC1) (C-Term) antibodyUIMC1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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RAP80 antibody can be used for detection of RAP80 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- RAP80 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- RAP80 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- UIMC1 (Ubiquitin Interaction Motif Containing 1 (UIMC1))
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别名
- RAP80
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背景
- RAP80 Antibody: RAP80 was initially identified as zinc-finger containing nuclear protein that is highly expressed in testis and interacts with the retinoid-related testis-associated receptor (RTR). Later experiments revealed that RAP80 is recruited by the Coiled-coil domain 98 (CCDC98) protein to the breast cancer-1 protein BRCA1, allowing the formation of BRCA1 foci in response to DNA damage caused by ionizing radiation. Both RAP80 and CCDC98 are required for DNA damage resistance, G2-M checkpoint control, and DNA repair. Cells depleted of either RAP80 or CCDC98 exhibited increased sensitivity to ionizing radiation, although not as much as in BRCA1-depleted cells, suggesting that RAP80 and CCDC98 control only part of the DNA damage response role of BRCA1. At least four isoforms of RAP80 are known to exist.
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基因ID
- 51720
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UniProt
- Q96RL1
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途径
- DNA Damage Repair, Nuclear Hormone Receptor Binding, Positive Regulation of Response to DNA Damage Stimulus
抗原
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