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MICA 抗体 (C-Term)

MICA 适用: 人, 小鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990765
发货至: 中国
  • 抗原 See all MICA 抗体
    MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
    抗原表位
    • 8
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 69
    • 18
    • 14
    • 11
    • 7
    • 4
    • 2
    • 1
    人, 小鼠
    宿主
    • 36
    • 33
    克隆类型
    • 36
    • 34
    多克隆
    标记
    • 44
    • 8
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MICA antibody is un-conjugated
    应用范围
    • 44
    • 37
    • 32
    • 19
    • 17
    • 12
    • 8
    • 8
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    MICA Antibody is affinity chromatography purified via peptide column.
    免疫原
    MICA antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human MICA. The immunogen is located within the last 50 amino acids of MICA.
    亚型
    IgG
    Top Product
    Discover our top product MICA Primary Antibody
  • 应用备注
    MICA antibody can be used for detection of MICA by Western blot at 0.5 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    MICA Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    MICA antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
    别名
    MICA (MICA 产品)
    别名
    MIC-A antibody, PERB11.1 antibody, MHC class I polypeptide-related sequence A antibody, MICA antibody
    背景
    MICA Antibody: Major histocompatibility complex (MHC) class I proteins are ubiquitously expressed and mediate the recognition of intracellular antigens by cytotoxic T cells. A related family, termed the MHC class I chain-related (MIC) proteins are recognized by NKG2D, a receptor on NK and T cells, and promote anti-tumor activity. MICA, a member of the MIC family, is widely expressed on many tumors, and it is the MICA/NKG2D interaction that is thought to stimulate the anti-tumor reactivity by T lymphocytes. Both MICA and MICB mRNA are widely expressed in normal tissues, with MICA being present in virtually every tissue except the nervous system, suggesting that MIC protein expression may only be one component of the anti-tumor activity of the immune system.
    分子量
    Predicted: 42 kDa

    Observed: 46 kDa
    基因ID
    4276
    NCBI登录号
    NP_000238
    UniProt
    Q29983
    途径
    Activation of Innate immune Response, Transition Metal Ion Homeostasis
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