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MICA 抗体 (C-Term)

The 兔 多克隆 anti-MICA antibody (ABIN6990765) specifically detects MICA in WB, ELISA, IF 和 IHC (p). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN6990765
发货至: 中国
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Quick Overview for MICA 抗体 (C-Term) (ABIN6990765)

抗原

See all MICA 抗体
MICA (MHC Class I Polypeptide-Related Sequence A (MICA))

适用

  • 102
  • 18
  • 14
  • 11
  • 7
  • 4
  • 2
  • 1
人, 小鼠

宿主

  • 44
  • 43
  • 17

克隆类型

  • 64
  • 37
  • 2
多克隆

标记

  • 63
  • 11
  • 8
  • 7
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MICA antibody is un-conjugated

应用范围

  • 50
  • 42
  • 38
  • 21
  • 20
  • 13
  • 8
  • 8
  • 6
  • 6
  • 5
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    纯化方法

    MICA Antibody is affinity chromatography purified via peptide column.

    免疫原

    MICA antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human MICA. The immunogen is located within the last 50 amino acids of MICA.

    亚型

    IgG
  • 应用备注

    MICA antibody can be used for detection of MICA by Western blot at 0.5 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    MICA Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    MICA antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    MICA (MHC Class I Polypeptide-Related Sequence A (MICA))

    别名

    MICA

    背景

    MICA Antibody: Major histocompatibility complex (MHC) class I proteins are ubiquitously expressed and mediate the recognition of intracellular antigens by cytotoxic T cells. A related family, termed the MHC class I chain-related (MIC) proteins are recognized by NKG2D, a receptor on NK and T cells, and promote anti-tumor activity. MICA, a member of the MIC family, is widely expressed on many tumors, and it is the MICA/NKG2D interaction that is thought to stimulate the anti-tumor reactivity by T lymphocytes. Both MICA and MICB mRNA are widely expressed in normal tissues, with MICA being present in virtually every tissue except the nervous system, suggesting that MIC protein expression may only be one component of the anti-tumor activity of the immune system.

    分子量

    Predicted: 42 kDa

    Observed: 46 kDa

    基因ID

    4276

    NCBI登录号

    NP_000238

    UniProt

    Q29983

    途径

    Activation of Innate immune Response, Transition Metal Ion Homeostasis, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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