ORAI3 抗体 (N-Term)
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北京 101111
Quick Overview for ORAI3 抗体 (N-Term) (ABIN6990743)
抗原
See all ORAI3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody is predicted to have no cross-reactivity to ORAI1 or ORAI2.
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纯化方法
- ORAI3 Antibody is affinity chromatography purified via peptide column.
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免疫原
- ORAI3 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human ORAI3. The immunogen is located within the first 50 amino acids of ORAI3.
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亚型
- IgG
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anti-ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) antibody
ORAI3 适用: 人 WB 宿主: 兔 Monoclonal 25GB4720 unconjugated Recombinant Antibody
anti-ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) (AA 1-30) antibodyORAI3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) (C-Term) antibodyORAI3 适用: 人, 小鼠 WB, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) (C-Term) antibodyORAI3 适用: 人, 大鼠 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 2H2G9 unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) (N-Term) antibodyORAI3 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3) (C-Term) antibodyORAI3 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ORAI3 antibody can be used for detection of ORAI3 by Western blot at 1 - 4 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL and Immunohistochemistry starting at 2 μ,g/mL
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunocytochemistry in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- ORAI3 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- ORAI3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- ORAI3 (ORAI Calcium Release-Activated Calcium Modulator 3 (ORAI3))
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别名
- ORAI3
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背景
- ORAI3 Antibody: Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI3 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. All three homologs have been shown to function as Ca++ plasma membrane channels gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor. However, ORAI3 channels failed to produce detectable Ca++ selective currents in cells co-transfected with ORAI3 and STIM1, indicating that ORAI3 channels undergo a lesser degree of depotentiation than ORAI1 or ORAI2. Na+ currents through ORAI1, 2 and 3 channels were equally inhibited by extracellular Ca++, indicating that each have similar affinities for Ca++ within the selectivity filter.
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基因ID
- 93129
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UniProt
- Q9BRQ5
抗原
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