SCO2 抗体 (C-Term)
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北京 101111
Quick Overview for SCO2 抗体 (C-Term) (ABIN6990718)
抗原
See all SCO2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- SCO2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- SCO2 antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human SCO2. The immunogen is located within the last 50 amino acids of SCO2.
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亚型
- IgG
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anti-SCO2 Cytochrome C Oxidase Assembly Protein (SCO2) (AA 1-130) antibody
SCO2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SCO2 Cytochrome C Oxidase Assembly Protein (SCO2) antibodySCO2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SCO2 Cytochrome C Oxidase Assembly Protein (SCO2) (AA 1-130) antibodySCO2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-SCO2 Cytochrome C Oxidase Assembly Protein (SCO2) (AA 42-266) antibodySCO2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-SCO2 Cytochrome C Oxidase Assembly Protein (SCO2) (AA 1-266) antibodySCO2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-SCO2 Cytochrome C Oxidase Assembly Protein (SCO2) (C-Term) antibodySCO2 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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SCO2 antibody can be used for detection of SCO2 by Western blot at 0.5 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- SCO2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- SCO2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- SCO2 (SCO2 Cytochrome C Oxidase Assembly Protein (SCO2))
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别名
- SCO2
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背景
- SCO2 Antibody: Synthesis of cytochrome c oxidase 2 was initially identified in yeast as one of two cytochrome c oxidase (COX) assembly proteins that enable the assembly of cytochrome c holoenzyme, a complex that catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. Like their yeast homologs, the function of both SCO2 and SCO1 are dependent on copper ion binding. Recent studies suggest that SCO2 expression is regulated by p53, so that a decrease in p53 expression, such as in numerous tumors and cells lines, the drop in SCO2 expression leads to a shift from normal aerobic respiration towards the production of glycolytic ATP. Defects in the SCO2 protein are also associated with fatal infantile cardioencephalomyopathy and COX deficiency.
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分子量
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Predicted: 29 kDa
Observed: 33 kDa -
基因ID
- 9997
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UniProt
- O43819
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途径
- Transition Metal Ion Homeostasis, Warburg Effect
抗原
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