SCO2 抗体 (AA 181-230)
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Quick Overview for SCO2 抗体 (AA 181-230) (ABIN7231290)
抗原
See all SCO2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 181-230
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原理
- Rabbit Anti-SCO2 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of SCO2 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human SCO2 protein at AA range: 181-230
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- SCO2 (SCO2 Cytochrome C Oxidase Assembly Protein (SCO2))
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别名
- SCO2
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背景
- Protein SCO2 homolog, mitochondrialCytochrome c oxidase (COX) catalyzes the transfer of electrons from cytochrome c to molecular oxygen, which helps to maintain the proton gradient across the inner mitochondrial membrane that is necessary for aerobic ATP production. Human COX is a multimeric protein complex that requires several assembly factors, SCO2 encodes one of the COX assembly factors. The encoded protein is a metallochaperone that is involved in the biogenesis of cytochrome c oxidase subunit II. Mutations in SCO2 are associated with fatal infantile encephalocardiomyopathy and myopia 6.
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分子量
- 29kD
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基因ID
- 9997
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UniProt
- O43819
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途径
- Transition Metal Ion Homeostasis, Warburg Effect
抗原
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