Kdm6b 抗体 (C-Term)
Quick Overview for Kdm6b 抗体 (C-Term) (ABIN6990705)
抗原
See all Kdm6b 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1370-1420, C-Term
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特异性
- This antibody is specific for JMJD3 and will not recognize other JMJD proteins.
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纯化方法
- JMJD3 Antibody is affinity chromatography purified via peptide column.
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免疫原
- Anti-JMJD3 antibody was raised against a peptide corresponding to 16 amino acids near the carboxy terminus of human JMJD3. The immunogen is located within amino acids 1370-1420 of JMJD3.
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亚型
- IgG
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anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (AA 265-450) antibody
Kdm6b 适用: 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (AA 1-30), (N-Term) antibodyKdm6b 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB10077 unconjugated
anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (AA 1-30) antibodyKdm6b 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (AA 1606-1641), (C-Term) antibodyKdm6b 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB10081-RB10082 unconjugated
anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (AA 1530-1682) antibodyKdm6b 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (AA 1023-1057) antibodyKdm6b 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB50943 unconjugated
anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (AA 879-912) antibodyKdm6b 适用: 小鼠 WB 宿主: 兔 Polyclonal RB51280 unconjugated
anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (AA 1613-1662) antibodyKdm6b 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (N-Term) antibodyKdm6b 适用: 人, 大鼠, 犬, Cow, 马, 兔, 猴, 豚鼠, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Lysine (K)-Specific Demethylase 6B (Kdm6b) (Middle Region) antibodyKdm6b 适用: 人, 小鼠, 大鼠, 犬, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 0.25-4 μ,g/mL, ICC: 2.5 μ,g/mL, IF: 20 μ,g/mL.
Antibody validated: Western Blot in human, mouse and rat samples, Immunocytochemistry in human samples, Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- JMJD3 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- JMJD3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))
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别名
- JMJD3
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背景
- JMJD3 Antibody: The Jumonji domain-containing protein 3 (JMJD3) functions as a trimethylation-specific demethylase, converting the trimethylated histone H3 Lys27 residue to the dimethylated form, and is thought to also function as a transcriptional repressor. JMJD3 plays a central role in regulation of posterior development, by regulating HOX gene expression. It is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation. JMJD3 can also interact with and demethylate p53, resulting in its stabilization and localization to the nucleus in mouse embryo fibroblasts during neural stem cell differentiation.
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分子量
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Predicted: 180
Observed: 180 kD kDa -
基因ID
- 23135
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UniProt
- O15054
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途径
- Warburg Effect
抗原
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