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DDX58 抗体

This anti-DDX58 antibody is a 兔 多克隆 antibody detecting DDX58 in WB, ELISA 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6990681
发货至: 中国

Quick Overview for DDX58 抗体 (ABIN6990681)

抗原

See all DDX58 抗体
DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))

适用

  • 76
  • 40
  • 15
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 68
  • 12
  • 1

克隆类型

  • 68
  • 13
多克隆

标记

  • 42
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DDX58 antibody is un-conjugated

应用范围

  • 67
  • 22
  • 21
  • 14
  • 14
  • 12
  • 10
  • 9
  • 7
  • 4
  • 4
  • 3
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 纯化方法

    RIG-1 Antibody is DEAE purified.

    免疫原

    RIG-1 antibody was raised against human GST-tagged RIG-1 protein.

    亚型

    IgG
  • 应用备注

    RIG-1 antibody can be used for the detection of RIG-1 by Western blot at 0.5 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

    Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human and rat samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    RIG-1 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    RIG-1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    DDX58 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58 (DDX58))

    别名

    RIG-1

    背景

    RIG-1 Antibody: The innate immune system detects viral infection by recognizing various viral components and triggers antiviral responses. Like the toll-like receptor 3 (TLR3), the cytoplasmic helicase retinoic acid inducible gene protein 1 (RIG-1) recognizes double-stranded (ds) RNA, a molecular pattern associated with viral infection. Unlike TLR3 however, RIG-1 activates the kinases TBK1 and IKKε, through the adaptor protein IPS-1. These kinases then phosphorylate the transcription factors IRF-3 and IRF-7 which are essential for the expression of type-I interferons. RIG-1 is required for the production of interferons in response to RNA viruses including paramyxoviruses, influenza virus, and Japanese encephalitis virus.

    基因ID

    23586

    UniProt

    O95786

    途径

    Activation of Innate immune Response, Hepatitis C
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