TIMD4 抗体 (AA 60-110)
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北京 101111
Quick Overview for TIMD4 抗体 (AA 60-110) (ABIN6990640)
抗原
See all TIMD4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 60-110
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特异性
- At least four isoforms of TIM-4 are known to exist, this antibody will detect all four isoforms.
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纯化方法
- TIM-4 Antibody is affinity chromatography purified via peptide column.
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免疫原
- TIM-4 antibody was raised against a 16 amino acid synthetic peptide from near the center of human TIM-4. The immunogen is located within amino acids 60 - 110 of TIM-4.
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亚型
- IgG
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anti-T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4) (AA 134-301) antibody
TIMD4 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4) (AA 333-361), (C-Term) antibodyTIMD4 适用: 人 WB 宿主: 兔 Polyclonal RB40431 unconjugated
anti-T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4) (C-Term) antibodyTIMD4 适用: 人, 小鼠, 大鼠 WB, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4) (Center) antibodyTIMD4 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4) antibodyTIMD4 适用: 小鼠 ELISA, FACS, IP, in vivo 宿主: 兔 Chimeric 5G3 unconjugated Recombinant Antibody
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应用备注
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TIM-4 antibody can be used for the detection of TIM-4 by Western blot at 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL and Immunohistochemistry starting at 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human and mouse samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- TIM-4 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- TIM-4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))
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别名
- TIM-4
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背景
- TIM-4 Antibody: The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. TIM-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, and this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM-1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.
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分子量
- Observed: 45 kDa
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基因ID
- 91937
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NCBI登录号
- NP_612388
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UniProt
- Q96H15
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途径
- Cancer Immune Checkpoints
抗原
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